Open Studies


Analgesics in the Pre-Hospital Setting: Implications on Hemorrhage Tolerance – Fentanyl

(IRB STU# 092017-069)

The Institute for Exercise and Environmental Medicine is currently seeking research subjects for a study examining the effects of different pain medications on blood loss.

Purpose

This study, which is funded by the U.S. Army Medical Research and Material Command, is being done to better understand the how fentanyl (pain medication) will alter the capacity to tolerate a serious injury leading to major blood loss in humans.

Requirements to participate

  • 18 – 45 years of age
  • Healthy & non-obese
  • Body weight greater than or equal to 143 pounds
  • English speaking
  • No current or previous cardiac, neurological and/or metabolic illness
  • No current or past history of substance or alcohol abuse

Participation will require 3 study visits lasting ~13 hours in total. During the study visits, subjects will be given pain medication and participate in a number exams that measure bodily function and pain tolerance. Qualified individuals will be compensated.

Contact Information

If you would like more information, please contact ieemthermoregulationTHD@TexasHealth.org at 214-345-6502.

Analgesics in the Pre-hospital Setting: Implications on Hemorrhage Tolerance - Morphine

(IRB STU# 092017-070)

Purpose

This study, which is funded by the U.S. Army Medical Research and Material Command, is being done to better understand how morphine (a commonly used pain medication) will alter the capacity to tolerate a serious injury leading to major blood loss in humans.

In the laboratory, we simulate blood loss by having individuals lay down with their lower body in a chamber and reducing the chamber pressure for a short period of time.

Requirements to participate

  • 18 – 45 years of age
  • Healthy & non-obese
  • Body weight greater than or equal to 143 pounds
  • English speaking
  • No current or previous cardiac, neurological and/or metabolic illness
  • No current or past history of substance or alcohol abuse

Participation will require 3 study visits lasting ~13 hours in total. During the study visits, subjects will be given pain medication and participate in a number exams that measure bodily function and pain tolerance. Qualified individuals will be compensated.

Contact Information

If you would like more information, please contact ieemthermoregulationTHD@TexasHealth.org at 214-345-6502.

Effects of Low Dose Ketamine on Cardiovascular Function

Purpose

Our research laboratory is looking for individuals to participate in a study examining how a commonly used pain medication affects heart and blood vessel function.

Eligibility

  • English speaking
  • 18 - 45 years of age
  • Non-obese
  • Systolic blood pressure <140 mmHg
  • Diastolic blood pressure <90 mmHg
  • No current or previous use of anti-hypertensive medications
  • No current or previous cardiac, respiratory, neurological, or metabolic illness
  • Any known history of renal or hepatic insufficiency/disease
  • Pregnancy or breast feeding
  • Not a current smoker
  • No current or past history of substance abuse

Study timeline

Participation requires three study visits lasting up to ~13 hours in total. Qualified participants will be compensated.

Contact Information

If you would like more information, please contact ieemthermoregulationTHD@TexasHealth.org at 214-345-6502.

Research Participants for the Thermal and Vascular Physiology Laboratory

The Thermal and Vascular Physiology Laboratory is recruiting healthy young and older individuals (18 - 80 years) to participate in our research studies.

To Participate in Research Studies age 60 to 80

  • We are currently seeking healthy, older adults to participate in research studies.
  • You cannot have any chronic illness such as high blood pressure or diabetes nor can you be a smoker.
  • Study procedures may include monitoring of your heart rate and rhythm, blood pressure monitoring, temperature monitoring and measurement of skin blood flow and perspiration.

To Participate in Research Studies age 18 to 55

  • We are currently seeking healthy adults to participate in research studies.
  • You cannot have any chronic illness such as high blood pressure or diabetes.
  • You must be a healthy weight, you cannot be a smoker, nor can you be pregnant or breast-feeding.
  • Study procedures may include monitoring of your heart rate and rhythm, blood pressure monitoring, temperature monitoring and measurement of skin blood flow and perspiration.

Qualified participants will be paid for their time.

Contact Information

If you would like more information, please contact ieemthermoregulationTHD@TexasHealth.org at 214-345-6502.

 

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