Pulmonary Physiology Laboratory

Our state-of-the-art research/clinical laboratory comprises:

  • A full service exercise physiology laboratory
  • A full service pulmonary function laboratory
  • A body composition laboratory including DEXA imaging

We are a nationally recognized clinical referral center for patients with unexplained shortness of breath on exertion 

For more information about diagnosis and treatment of unexplained shortness of breath on exertion, please visit the Dyspnea on Exertion Clinic

Dyspnea on Exertion in Obesity:

  • Perceived breathlessness is a common complaint of many obese individuals.
  • Determination of ventilatory limitations during exercise remains an important clinical issue.
  • By examining the ventilatory response to exercise, in combination with measures of respiratory mechanics and cardiovascular function, we are able to investigate the importance of respiratory constraints in exercise ventilatory limitation in cardiopulmonary patients.

By testing pulmonary function, exercise capacity, respiratory mechanics, work of breathing, and body composition, we are able to identify connections between physiological markers, respiratory mechanics, and shortness of breath on exertion.

Cardiopulmonary Exercise Testing:

  • Determination of ventilatory limitations during exercise remains an important clinical issue.
  • By examining the ventilatory response to exercise, in combination with measures of respiratory mechanics and cardiovascular function, we are able to investigate the importance of respiratory constraints in exercise ventilatory limitation in cardiopulmonary patients.

The focus of the Pulmonary Physiology Laboratory is the study of integrated cardiorespiratory responses to exercise in humans.

NIH funded research topics in the Pulmonary Physiology Laboratory include:

  • Normal aging
  • Obesity
  • Cardiopulmonary disease
  • Ventilatory control during exercise
  • Clinical cardiopulmonary exercise testing
    • We are currently investigating children, obesity and the effects it has on their respiratory function, exercise tolerance and dyspnea on exertion.
    • Our overall goal is to find better approaches regarding the prevention, care, and treatment of exertional dyspnea in obesity.

Current Projects

  • Respiratory Effects of Obesity in Children: How does obesity effect respiratory function, dyspnea on exertion and exercise tolerance? (funded by the NIH – NHLBI)
  • Pulmonary Mechanisms of Dyspnea in HFpEF: In patients with heart failure with preserved ejection fraction, does obesity effect pulmonary mechanisms? (funded by the NIH – NHLBI)
  • Shortness of Breath during Exertion in Older Adult with Obesity: In older adults, shortness of breath is increased subjective perception cause is unknown.
  • Mechanical Unloading in Older Obese Adults: In older obese adults, will mechanical unloading of the chest wall help in respiratory function and exercise tolerance?

Current Research Opportunities

View our current Pulmonary Physiology research opportunities for:

Researchers

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Publications

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